Pathogenesis of Disseminated Intravascular Coagulation (DIC)

• Consumptive Coagulopathy
• Widespread coagulation leading to thrombin formation all over body and consumption of all platelets and coagulation factors.
• Everything is consumed, and there are thrombi all over body.
• Bleeding and vessel occlusion at the same time

• Which LAB parameters will be abnormal???
• All that you can think of….
• Bleeding time, PT, aPTT, D-dimer, Fibrin Split Products